Earthquake is one ofmost serious natural disasters in theworld. Ithaswide geographic coverage, huge dam-age, and long tmi e influence for recovery. The earthquake happened inWenchuan onMay12, 2008 caused greatdamage in 42 counties in Sichuan province, 23 counties in Gansu province, and 19 counties in Shaanxi province. In addition, it also hasmuch influence on Chongqing, Yunnan, Shanx,i Guizhou, andHubei provinces. Because of the severely destroyed in frastructures, complicated topography and badweather condition after the earthquake, the disaster situation assessment from ground investigation is very difficult to undertake. In this situation, feasible approaches should be investigated.In this paper, we take the remote sensingmonitoring and assessment of theWenchuan Earthquake disaster situation as a case study and discuss the technical approaches and methods on application of space and airborne remote sensing technology for earthquake disaster situationmonitoring and assessment.Firstly, by integratingmulti-platformmulti-sensordata, we defined the earthquake disaster situationmonitoring inde-xes according to two differentdisasterseverity levels. Forareaswith high-leveldisaster loss, aerialphotos and high-resolu-tion satellite mi ageswith less than 1meter resolution are used as themajordata sources, where fourmajor categorieswith detailed subclasses are classified, .i e.,1)urban and rural residential areas;2)urban and rural infrastructures such as industrial andmining lands, highways, railways, bridges, tunnels, electric facilities, telecommunication facilities, chan-nels, dikes, reservoirs, and dams;3)geological and environmental change information such as earthquake lakes, rock slumps, landslides, and turbidities; and 4) destroyed farmlands such as croplands and forest lands. For areaswith low-level disaster loss, high andmedium resolution optical and SAR satellite mi ages before and after the earthquake are used as themajordata sources, where fourmajor categorieswith lessdetailed subclasses are classified,.ie.,1)urban and ru-ral residential areas; 2) urban and rural infrastructures such as industrial and mining lands, highways, railways, and large reservoirs;3)geological and environmental change information such as earthquake lakes, rock slumps, landslides,and turbidities; and 4) destroyed farmlands such as croplands and forest lands.By combining themulti-tempora,l multi-source data before and after the earthquake, we establish the technical flows for quick geometric processing, quick data quality analysis and assessment, quick change detection, quick target interpre-tation, quick spatial risk assessment for landslides induced by earthquake, and the synthesis of thesemethods fordisaster monitoring. For geometric processing, the Image Info softwaremodule Pixel Grid isused.For mi age fusion, the data fusion module of ImageInfo isused. For interpretation ofdifferentarea of mi ages, theArcGIS software isused. Additionally, the SINMAP module underArcGIS software is also used for the validation of the extracted geological risk areas. The approach has been successfully applied inmonitoring, mapping, and statistical assessmentof the earthquake disaster situation.In addition, we also develope an application system which could provide functionalities fordisaster informationman-agement, visualization, and statisticalanalysis. Itutilize 2D Web GIS user interface and 3D virtual smi ulation environment tomanage the disasterdatabase and visualize themonitored results as 2D maps, statistic tables, graphs, and 3D models,and provide functionalities formeasure and analysis.Finally, we also addressed and discussed some practical problemswhen applying this approach that should be well justified in the future, including the development of new geometric correction algorithm without control points, and the\nstandardization of theworkflow described in this paper forbetter accuracy.