According to investigation results based on remote sensing technology, This paper discusses the patterns of Cele oasis desertification dynamic change in the south of Tarim Basin. Considering macroscopical research, this paper chooses 4 main land cover types which are desertification, oasis, Ecotone and water body, and they represent distinct characteristics of the local area. To register 3 different time, spatial resolution and spectral resolution satellite images, the paper uses some GCPs registered accurately 3 satellite images (for MSS, TM, SPOT HRV) and fuses a image with these multi_source data. The fusion image shows more details than mono_time image and plays a assistant revising role to some dynamic change charts as followings. On the basis of field survey and some statistical data, the paper uses PCI soft ware to process these data and produces a series of 4 main land cover dynamic change charts. Through analyzing these charts, the paper has studied the dynamicly distributed data of land covers spanning 21 years and the regulation of the local ecological environmental system. At last the paper points out that the trend of Cele region oasis desertification expansion is derived from two important reasons which have severe influences of nature and humanity. Therefore, in order to ameliorate the local ecological environment, people living in Cele country should work hard to plant more to preserve their homeland and reduce the degree of sandy wind offensive, to develop social economy, and to carry out sustaining development.